Diabetes Care Twice Daily

Diabmexa M 500

Metformin Hydrochloride IP 500 mg Tablets

First-line oral hypoglycemic powered by the Adaptive Adherence Intelligence Engine

500
mg

Film-coated tablets for oral administration

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Drug Information

Composition

Metformin HCl IP

500 mg per tablet

Category

Biguanide

Oral Hypoglycemic Agent

Pack Size

10 Tablets

Blister pack, 10x10

Storage

15-25°C

Protect from moisture & light

Drug-Food Interactions

Alcohol

Metformin + alcohol increases risk of lactic acidosis — a rare but life-threatening condition. Alcohol also causes hypoglycemia and masks warning symptoms. Avoid completely or strictly limit.

High-Fat Meals

Delays metformin absorption by 35% and reduces peak plasma concentration. Take with low-fat meals for consistent glucose control.

Iodinated Contrast Media

Must discontinue 48 hours before and 48 hours after contrast studies. Risk of acute kidney injury and lactic acidosis.

Vitamin B12-Rich Foods (Long-term)

Metformin reduces B12 absorption by 30% over time. While B12 foods are healthy, monitor serum B12 annually. Consider supplementation after 2+ years.

High-Fiber Foods (Recommended)

Oats, lentils, vegetables slow glucose absorption, complementing metformin's mechanism. Best taken together with medication.

Cinnamon & Fenugreek

Natural insulin sensitizers that may enhance metformin efficacy. Add to breakfast taken with morning dose.

Circadian Dosing Schedule

6-8 AM

🌅 Morning Dose — With Breakfast

Take 1 tablet with breakfast. Metformin reduces hepatic glucose production which peaks in dawn phenomenon (4-8 AM). Taking now targets this surge.

With food (mandatory) Full glass of water
12-2 PM

🌞 Midday — Glucose Monitoring

No dose. Check post-prandial glucose if possible. Eat balanced lunch with complex carbs, protein, and fiber.

Check PPBS
6-8 PM

🌆 Evening Dose — With Dinner

Take 1 tablet with dinner. Controls nocturnal hepatic glucose output. Never take on empty stomach — severe GI distress risk.

With dinner Never empty stomach
10 PM

🌙 Night — Fasting Window

No medication. Metformin's half-life (6.2h) from evening dose maintains coverage overnight. Check fasting glucose in morning.

Fasting glucose check

Adaptive Adherence Intelligence Engine

Your personal AI companion for Diabmexa M 500. Scan the QR code on your packaging to unlock voice-guided dosing, food interaction alerts, WhatsApp reminders, and daily vitals tracking.